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Angiotensin I Converting Enzyme Activity (ACE1) Assay Kit (Fluorometric), BioVision Inc.

Supplier: BioVision
K227-100
Industry's first kit to detect ACE1 activity in biological samples.

  • Simple one-step reaction
  • Takes only one to two hours
  • Non-radiometric fluorescent detection
  • HTP adaptable

Angiotensin I converting enzyme (ACE1, EC: 3.4.15.1), a dipeptidyl carboxypeptidase, is part of the renin-angiotensin system (RAS) that controls regulation of blood pressure by cleaving the C-terminal dipeptides of angiotensin I and bradykinin. It is found on the luminal surface of vascular endothelial cells, especially in pulmonary tissues. Elevated levels of ACE1 are found in patients suffering from sarcoidosis, leprosy, hyperthyroidism, acute hepatitis, primary biliary cirrhosis, diabetes mellitus, multiple myeloma, osteoarthritis, amyloidosis, Gaucher’s disease, pneumoconiosis, histoplasmosis and miliary tuberculosis. BioVision’s ACE1 Activity Assay Kit utilizes an active ACE1 to cleave a synthetic o-aminobenzoyl peptide (Abz-based peptide) substrate to release a fluorophore. The released Abz can be easily quantified using a fluorescence microplate reader. This assay kit is simple, rapid and can detect ACE activity as low as 10 mU in biological samples.




 

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Description Size Supplier No. VWR Catalog Number Unit Price Quantity
Angiotensin I Converting Enzyme Activity (ACE) Assay Kit (Fluorometric) 100 Assays K227-100 75836-724 Each Retrieving

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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