IBSMM1842

M1842
102971-860EA 396 USD
102971-860
IBSMM1842
Widely used carbocyanine dye.

  • Ratiometric indicator of mitochondrial potential

Upon mitochondrial depolarization JC-1 exhibits a potential-sensitive color shift from red to green, due to concentration-dependent monomerization of red fluorescent J-aggregates. It has been used to detect the collapse of mitochondrial membrane potential in functional assays of multiple drug resistance and in apoptosis-related mitochondrial membrane potential measurements.
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