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Brominated analog of carboxyfluorescein that is a useful photosensitizer and singlet oxygen generator.

  • Useful for ROS studies

Carboxyeosin has a singlet oxygen yield that is approximately 19 times greater than that of fluorescein. Using this property, CE has been found to be useful for photoconverting diaminobenzidine (DAB) as a method for improving resolution for immunoprecipitation or in situ hybridization techniques in light and electron microscopy. Upon excitation, carboxyeosin labeled probes can be used to generate singlet oxygen, which in turn will oxidize DAB into an opaque precipitate within cells. The resulting DAB reaction provides a nondiffusible staining method for monitoring hybridization or antibody localization in cells and tissues.

Formula: C₄₂H₁₆Br₈O₁₄
MW: 1383.808 g/mol
CAS Number: 132201-84-4



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100 mg M1300 101447-545 Each (100mg) Retrieving Restricted
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