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6-p-Toluidino-2-naphthalenesulfonic acid, potassium salt


Fluorescent probe for conformational studies and for use in quantitation of hydrophobic proteins.

  • Protein label
  • More water soluble than TNS free acid

Protein folding, conformational changes or other processes that modify the exposure of the probe to water can be monitored using this environmentally sensitive dye. TNS is a fluorescent probe useful for measuring conformational changes and quantitative studies of protein hydrophobicity. It is practically nonfluorescent in water, becoming fluorescent when bound to membranes (q.y. ~0.27) or hydrophobic domains of proteins (q.y. ~0.72). The fluorescence is also enhanced by cyclodextrins, permitting a sensitive method for separating and analyzing cyclodextrins with capillary electrophoresis. This potassium salt of TNS is more water soluble than the free acid.

Formula: C₁₇H₁₄KNO₃S
MW: 351,461 g/mol
CAS Number: 32752-10-6

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 mg M0720 101176-320 Each (100mg) Retrieving Restricted
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