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D-erythro-Sphingosine-1-phosphate

Supplier: MilliporeSigma

A putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway.

Activates phospholipase D (PLD) and inhibits chemotactic motility and invasiveness of tumor cells. Also stimulates growth of quiescent Swiss/3T3 fibroblasts. Inhibits activation of caspases that cleave PARP and lamins during Fas- and ceramide-mediated apoptosis.

Formula: C₁₈H₃₈NO₅P
MW: 379,478 g/mol
MDL Number: MFCD00274457
CAS Number: 26993-30-6
Specification Test Results
Form White Solid
Chemical formula C18H38NO5P
Hygroscopic Hygroscopic
Reversible N
Primary Target Mobilizes calcium from intracellular stores
Purity ≥95% by TLC
Cell Permeable N
Toxicity Irritant
Storage -20 °C
Hygroscopic Hygroscopic
Do not Freeze Ok to Freeze
Special Instructions Reconstitution, aliquot and evaporate under a stream of nitrogen
Usage Prior to use, dissolve in 4 mg/ml BSA solution with vortexing
Life Stock solutions are stable for up to 2 months at -20°C
Package Packaged under Inert gas


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Size Packaging Supplier No. VWR Catalog Number Unit Price Quantity
1 mg Glass Bottle 567727-1MG 80054-486 Each (1mg) Retrieving Restricted
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