Carbonate resin (MP), beads, macroporous 330-1225 µm, 15-50 mesh (>90% within) Loading: 2.5-2.8 mmol/gSupplier: Supra Sciences
Versatile basic reagent useful for scavenging excess acidic reagents and byproducts generated during reactions. Very effective in freebasing amine salts produced during HPLC purification.
Carbonate Resin, MP, is a macroporous resin functionalized with a tetraalkylammonium carbonate end group. It is a widely utilized basic reagent for the quenching and neutralization of acidic media derived from a variety of organic transformations and purification techniques. It is highly effective in freebasing amines isolated from an acid buffered HPLC purification. This allows researchers to proceed confidently knowing that any acid sensitive functionality will remain unaltered during concentration and/or storage. Carbonate has also shown significant utility in amide coupling reactions by scavenging a variety of acidic molecules including carboxylic acids, acidic phenols and HOBT. The simple filter and concentrate protocols which result from incorporating MP-CO3 allows one to generate reactions, which require no exposure to water. This reduces the likelihood of losing precious small molecules in aqueous environments. It has also found use in ether synthesis, providing products simply via
Specification Test Results
|Particle size||330-1225 μm (15-50 mesh)|