S100B Human ELISA, BioVendor

Supplier: BioVendor
RD192090100
101215-602EA 735.23 USD
101215-602
S100B Human ELISA, BioVendor
Assays ELISAs
S100B is abundant in the nervous system where it is predominantly expressed in astrocytes, oligodendrocytes and Schwann cells.

  • Calibration Range: 10-320 pg/mL
  • Limit of Detection: 10 pg/mL
  • Cerebrospinal fluid, Serum: 25 uL/well

S-100B protein is a member of highly homologous acidic calcium and zinc binding proteins family (S100 family) that possess two EF-hand motifs. S100B is a homodimer with the molecular weight 21 kDa. S100B is abundant in the nervous system where it is predominantly expressed in astrocytes, oligodendrocytes and Schwann cells. S100B is released from brain tissue into cerebrospinal fluid (CSF) and blood following brain damage of different origin, i.e., brain infarction, intracerebral or subarachnoidal hemorrhage, neurotrauma and large intracerebral tumors. It is documented a relationship between degree of cell damage and S100B levels in CSF. Also patients with progressive melanoma disease show elevated serum concentrations of S100B.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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