sCD40L Human ELISA, BioVendor

Supplier: BioVendor
RAF093R
102552-134EA 1054.98 USD
102552-134
sCD40L Human ELISA, BioVendor
Assays ELISAs
CD40/CD40L interactions are essential for T-cell-dependent B cell proliferation and differentiation, for activation of antigen presenting cells and for cytokine production on numerous other cells.

  • Calibration Range: 0.16-10 ng/mL
  • Limit of Detection: 0.06 ng/mL
  • Cell culture supernatant, Plasma, Serum: 20 uL/well

CD40 belongs to the TNF receptor superfamily. A key role of CD40/CD40ligand interactions in immune activation, particularly in T-cell dependent B cell responses is anticipated. This molecule as well as the other ligands of the family share the property of co-stimulation of T-cell proliferation and are all expressed by activated T-cells.Because the ligand of CD40 (CD40L) is expressed on activated T helper cells, B cells may escape from apoptosis and are activated when the immune system interacts with foreign antigens, which are normally able to activate T-helper cells. Thus the CD40/CD40L interaction plays a central role in the various phases of the B cell response to T-dependent antigens.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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