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Recombinant Human FGF-acidic, MP Biomedicals

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 16.0 kDa protein consisting of 141 amino acid residues.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 µg 08P984301 10496-944 Each (10µG) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name FGF Acidic
Protein Synonyms ECGF-beta, HBGF-1, Fibroblast Growth Factor-acidic, FGF-1
Protein/Peptide Type Recombinant
Source E. coli
Sequence MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Endotoxin Content <0.1 ng/µg of protein (<1EU/µg)
Protein Type Recombinant
Specific Activity Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10 ng/mL, corresponding to a specific activity of ≥ 1 x 10^5 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/mL in the presence of 10 µg/mL heparin, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
Reactivity Pig, Mouse, Bovine, Shark, Squid, Rat
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