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Recombinant Human BMP-4, MP Biomedicals

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. E.coli derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
2 µg 08P983681 10496-936 Each (2µG) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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SPECIFICATIONS

Protein/Peptide Name BMP4
Protein Synonyms BMP-2B
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Sequence KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS mLYLDEYDKV VLKNYQEMVV EGCGCR
Endotoxin Content 0.1 ng/µg of protein (1EU/µg)
Protein Type Recombinant
Specific Activity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/mL.
Reactivity Mouse
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