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Recombinant Human FGF-8, MP Biomedicals

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8 (FGF-8b) is a 22.5 kDa protein consisting of 194 amino acid residues.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
5 µg 08P984271 10496-948 Each (5µG) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name FGF8
Protein Synonyms HBGF, Fibroblast Growth Factor-8, FGF-8b, AIGF
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Sequence MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR
Endotoxin Content <0.1 ng/µg of protein (<1EU/µg)
Protein Type Recombinant
Specific Activity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/mL, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
Reactivity Chicken, Mouse, Rabbit, Rat
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