Caspase Drug Screening Kit, PromoKine

Supplier: PromoKine
PromoKine
PK-CA577-K157 PK-CA577-K151 PK-CA577-K159 PK-CA577-K155 PK-CA577-K160 PK-CA577-K158 PK-CA577-K154 PK-CA577-K152 PK-CA577-K153 PK-CA577-K156
10183-468EA 808.7 USD
10183-468 10183-466 10183-478 10183-640 10183-464 10183-476 10183-462 10183-474 10183-472 10183-470
Caspase Drug Screening Kit, PromoKine
Drug Tests
Caspase Drug Screening Kits for effective screening of caspase inhibitors using fluorometric methods.

  • Assays are simple, straightforward
  • Can be performed directly in microtiter plates
  • Optimal conditions to obtain maximal activity

Inhibition of caspases has been shown to delay apoptosis, implicating a potential role in drug screening efforts. PromoKine provides a full line of Caspase Drug Screening Kits for effective screening of caspase inhibitors using fluorometric methods. The assays utilize peptide substrates containing consensus cleavage sequences specific for each caspase, labeled with AFC (7-amino-4-trifluoromethyl coumarin). Active caspases (provided in the kits) cleave the synthetic substrates to release free AFC which can then be quantified using a microtiter plate reader. Compounds to be screened can directly be added to the reaction and the level of caspase inhibition can then be determined. The assays are simple, straightforward, and can be performed directly in microtiter plates. Assay conditions for each caspase have been optimized to obtain the maximal activity.
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