Human Recombinant LTbetaR Non-lytic (from CHO Cells)

Supplier: ProSci
90-536
75794-434EA 700.26 USD
75794-434
Human Recombinant LTbetaR Non-lytic (from CHO Cells)
Proteins and Peptides
The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines, and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.

  • Fusion-Tag: Fc Tag

This recombinant proteins is for research use only.
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR