Human Recombinant PARP3 (from Insect Cells (Sf21))

Supplier: ProSci
90-342
75794-150EA 606.79 USD
75794-150
Human Recombinant PARP3 (from Insect Cells (Sf21))
Proteins and Peptides
PARP-3 [ARTD3] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

  • Fusion-Tag: His Tag

This recombinant proteins is for research use only.
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR