Mouse Recombinant IDO (from E. coli)

Supplier: ProSci
90-017
75793-540EA 870.03 USD
75793-540
Mouse Recombinant IDO (from E. coli)
Proteins and Peptides
IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.

  • Fusion-Tag: His Tag

This recombinant proteins is for research use only.
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