Mouse Recombinant Frizzled 2

Supplier: ProSci
92-604
75791-770EA 524.61 USD
75791-770
Mouse Recombinant Frizzled 2
Proteins and Peptides
Wnt signaling plays a critical role in embryonic development, and genetic aberrations. Frizzled2 (Fzd2) is a receptor for wingless-type MMTV integration site family members (Wnts), the aberrant overexpression of which has been noted to contribute to cancer metastasis. Frizzled2 (Fzd2) and its ligands Wnt5a/b are elevated in metastatic liver, lung, colon, and breast cancer cell lines and in high-grade tumors and that their expression correlates with markers of epithelial-mesenchymal transition (EMT). It is also shown that Frizzled-2 expression is greater in embryonic than adult tissues, with heart, brain, lung, kidney and gut showing the highest levels.

  • Fusion-Tag: C-Fc tag

This recombinant protein can be used for biological assays. For research use only.
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