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p27 Recombinant Protein, Prosci

Supplier: Prosci
91-268
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skeletal muscle. CDKN1B is a potent inhibitor of Cyclin E- and Cyclin A-CDK2 complexes. CDKN1B forms a complex with Cyclin Type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. In addition, CDKN1B acts as an inhibitor or an activator of Cyclin Type D-CDK4 complexes depending on its phosphorylation state and stoichometry.

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: N-6 His tag




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.05 mg 91-268 75789-212 Each (50µG) Retrieving

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Protein/Peptide Name p27
Protein Synonyms KIP1, p27Kip1, Cyclin-Dependent Kinase Inhibitor p27, Cyclin-Dependent Kinase Inhibitor 1B, CDKN1B
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Sequence Met1-Thr198
Purity > 95% as determined by reducing SDS-PAGE
Endotoxin Content <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Molecular Weight 24.2 kD
Formulation Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Conditions Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Tested Applications For Biological Assays
Protein Type Recombinant
Modification N-6 His tag
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