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TNF beta Recombinant Protein, Prosci

Supplier: Prosci
91-161
Tumor Necrosis Factor beta (TNF- beta ) is a secreted protein belonging to the tumor necrosis factor family. TNF- beta binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF- beta forms heterotrimers with lymphotoxin-beta, which anchors TNF- beta to the cell surface. TNF- beta mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF- beta is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.

This recombinant protein can be used for biological assays. For research use only.




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.05 mg 91-161 75789-038 Each (50µG) Retrieving

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Protein/Peptide Name TNF beta
Protein Synonyms TNFSF1, LTA, LT-Alpha, Tumor Necrosis Factor Ligand Superfamily Member 1, TNFB, TNFSF1B, Lymphotoxin-Alpha, TNF-Beta
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Sequence Leu35-Leu205
Purity > 95% as determined by reducing SDS-PAGE
Endotoxin Content <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Molecular Weight 18.8 kD
Formulation Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Conditions Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Tested Applications Bioassay
Protein Type Recombinant
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