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beta-Defensin 1 Recombinant Protein, Prosci

Supplier: Prosci
beta -Defensin 1 (DEFB1) is a member of the beta -defensin family, which is highly expressed by epithelial cells. beta -defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. beta -defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta -defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in beta -Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. beta -defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, beta -defensin 1 is associated with induction profiles in gingival keratinocytes.

This recombinant protein can be used for biological assays. For research use only.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.05 mg 91-108 75788-932 Each (50µG) Retrieving

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Protein/Peptide Name beta-Defensin 1
Protein Synonyms Defensin Beta 1, Beta-Defensin 1, HBD1, BD-1, DEFB1, BD1, hBD-1
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Sequence Gly22-Lys68
Purity > 95% as determined by reducing SDS-PAGE
Endotoxin Content <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Molecular Weight 5.07 kD
Formulation Lyophilized from a 0.2 um filtered solution of 20mM PB, 130mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Conditions Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Tested Applications For Biological assays
Protein Type Recombinant
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