CellExp™ Human Recombinant FGF4 (from Cells)

Supplier: BioVision
6449-50 6449-10
10008-614EA 863.96 USD
10008-614 10008-612
CellExp™ Human Recombinant FGF4 (from Cells)
>95% Pure HEK 293 cells expressed Human recombinant FGF-4

ED₅₀ is typically 0.25 to 1.25 ng/mL. The specific activity was determined by the dose- dependent stimulation of the proliferation of the Balb/3T3 cell line.

FGF4 is involved in mitogenic and cell survival activities and takes part in a range of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF4 possess oncogenic transforming activity. FGF4 and FGF3, oncogenic growth factors are localized on chromosome 11. Co-amplification of both factors was found in several kinds of human tumors. FGF4 functions in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Human FGF-4 shares high homology and cross-reactivity with the mouse protein.
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