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Human CellExp™ BMP-4, Human Recombinant, BioVision

Supplier: BioVision
6445-50 6445-10
>95% Pure HEK 293 cells expressed Human recombinant BMP-4

ED₅₀ is typically 2 to 10 ng/mL. The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).

BMP4 belongs to the transforming growth factor-beta (TGFβ) superfamily. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-4 plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 6445-10 10008-596 Each (10µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

50 μg 6445-50 10008-598 Each (50µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

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SPECIFICATIONS

Protein/Peptide Name BMP4
Protein Synonyms BMP4, ZYME, BMP2B1, BMP2B BMP4, BMP2B1, BMP2B, ZYME
Protein/Peptide Type Recombinant
Species Human
Source 293 cells
Purity ≥95%
Endotoxin Content < 1.0 EU per 1 μg of protein
Molecular Weight 34 kDa
Formulation Lyophilized from a PBS solution.
Reconstitution Instructions Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.
Protein Type Recombinant
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