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Human CellExp™ BMP-2, Human Recombinant, BioVision

Supplier: BioVision
6444-50 6444-10
>95% Pure HEK 293 cells expressed Human recombinant BMP-2

ED₅₀ is typically 20 to 100 ng/mL. The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).

BMP2 belongs to the transforming growth factor-beta (TGFβ) superfamily. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. BMP-2 is expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary, and small intestine. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva. BioVision’s BMP-2 is produced in a serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media and other applications.




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 6444-10 10008-592 Each (10µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

50 μg 6444-50 10008-594 Each (50µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Protein/Peptide Name BMP2
Protein Synonyms BMP-2, BMP2A
Protein/Peptide Type Recombinant
Species Human
Source 293 cells
Purity ≥95%
Endotoxin Content < 1.0 EU per 1 μg of protein
Molecular Weight 30 to 38 kDa
Formulation Lyophilized from a solution of 50 mM sodium acetate, pH 4.5, with 50 mM NaCl.
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Protein Type Recombinant
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