CellExp™ Human Recombinant Activin A (from Cells)

Supplier: BioVision
CellExp™
AB285725-10UG AB285725-50UG
10008-586EA 5262.99 USD
10008-586 10008-584
CellExp™ Human Recombinant Activin A (from Cells)
Proteins and Peptides
>95% Pure HEK 293 cells expressed Human recombinant Activin A

ED₅₀ is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent inhibition of proliferation of the MPC-11 cell line (mouse plasmocytoma cell line).

Activins are homodimers or heterodimers of the different subunit isoforms, part of the TGF-β super-family. Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. BioVision’s Activin A is
produced in a serum-free, chemically defined media.
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