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Human recombinant UBE2R1 (CDC34), BioVision

Supplier: BioVision
6436-3
>95% Pure Human recombinant UBE2R1 (CDC34)

Protein concentration of 100 nM - 1 µM is recommended for in vitro conjugation.

UBE2R1 is important in the control of cell cycle and DNA replication. In association with different E3 complexes, including SCF, it has been shown to target many different substrates for ubiquitination and degradation during cell division, signal transduction, and development. UBE2R1 substrates include B-Myb, Wee1, MyoD, ATF5, p27Xic1, and p27Kip1. Additionally, substrates such as p21Cip1, E2F, cyclin E, and cyclin D are putative substrates of UBE2R1 by virtue of their SCF requirement for proteolysis. This protein is useful for in vitro ubiquitinylation reactions.




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
3 n mol 6436-3 10008-572 Each (3Nmo) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Protein/Peptide Name UBE2R1
Protein Synonyms CDC34
Protein/Peptide Type Recombinant
Species Human
Purity ≥95%
Molecular Weight 27.730 kDa
Formulation 75 µL of a 40 µM solution (3 nmoles) in 50 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol.
Protein Type Recombinant
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