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Human recombinant UBE2D3, BioVision

Supplier: BioVision
6430-3
>95% Pure Human recombinant UBE2D3 (UbcH5c)

Typical enzyme concentration of 100 nM - 1 mM is used for in vitro conjugation, depending on conditions.

UBE2D3 (UbcH5b) is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. The UbcH5 family (including UbcH5a and UbcH5c, having 88% and 89% sequence identity with UbcH5b respectively) are the human homologues of the Saccharomyces cerevisiae UBC4/5 family (~79% sequence identity). Members of the UbcH5 family have been implicated in a number of inflammatory and cancer pathways including the ubiquitylation of p53 and IκBα with the help of different E3 ligases (Hdm2 and SCF complexes respectively).




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
3 n mol 6430-3 10008-044 Each (3Nmo) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Protein/Peptide Name UBE2D3
Protein Synonyms UBE2D3. Gene ID: 7323, MGC43926, MGC5416, UBCH5C, UBC4/5
Protein/Peptide Type Recombinant
Species Human
Gene ID 7323
Purity ≥95%
Molecular Weight 28.707 kDa
Formulation 75 µL of a 40 µM solution (3 nmoles) in 25 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol.
Protein Type Recombinant
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