Midkine, murine recombinant, BioVisionSupplier: BioVision
10009-282EA 632.83 USD10009-282 10009-280
Midkine, murine recombinant, BioVision
Proteins and Peptides
>98% Pure active Murine Recombinant Midkine.
Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml.
Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorigenesis. Recombinant murine Midkine is a 13.3 kDa protein containing 120 amino acid residues including five intra-molecular disulfide bonds.