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GMF-beta, human recombinant, BioVision

Supplier: BioVision
4880-1000 4880-10
>98% Pure Recombinant human GMF-beta.

Glia Maturation Factor-Beta (GMF-Beta) is a 17 kDa protein nerve growth factor identified as a growth and differentiation factor in the vertebrate brain.Glia Maturation Factor-Beta stimulates differentiation of normal neurons as well as glial cells. GMFB inhibits the proliferation of the N-18 neuroblastoma line and the C6 glioma line while promoting their phenotypic expression.
GMF-beta enhances the phenotypic expression of glia & neurons thus inhibits the proliferation of their respective tumors when added to cell culture. Cell- surface GMF-Beta acts on the target cells at close range when cells are in direct contact. GMF-Beta is produced by thymic epithelial cells and plays an important role in T cell development in favor of CD4+ T cells.
GMF-Beta is a brain-specific protein which belongs to the actin-binding proteins (ADF) family. GMF-beta appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines.




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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 4880-10 10007-268 Each (10µG) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

1 mg 4880-1000 10007-270 Each (1mg) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

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SPECIFICATIONS

Protein/Peptide Name GMFB
Protein Synonyms GMF-beta, GMF, GMFB, Glia maturation factor beta, GMF-B GMF, GMF-beta, Glia maturation factor beta, GMFB, GMF-B
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Purity ≥98%
Molecular Weight 17.0 kDa
Formulation Lyophilized after dialysis against 20 mM PBS pH 7.4 and 130 mM NaCl.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile H₂O to a concentration ≥ 100 µg/ml.
Protein Type Recombinant
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