Human Recombinant Ctgfl (from E. coli)

Supplier: BioVision
7129-10 7129-50
10009-176EA 198.47 USD
10009-176 10009-178
Human Recombinant Ctgfl (from E. coli)
>95% Pure active Human Recombinant CTGFL/Wisp2.

Determined by its ability to inhibit IGF-II induced proliferation of MCF-7. The expected ED50 is between 10-20 ng/ml in the presence of 15 ng/ml of human IGF-II.

CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.
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