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sCD23, Human Recombinant, BioVision

Supplier: BioVision
>96% Pure active Human Recombinant sCD23.

Measured by its ability to induce TNF-alpha production by human PBMCs.

CD23, the low affinity receptor for IgE, belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane bound CD23. The predominant soluble form of CD23 (sCD23) consists of 172 amino acids corresponding to the extracellular domain of the full length precursor. sCD23, in addition to binding IgE, also exerts a number of IgE independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes. Recombinant human sCD23 is a 19.2 kDa non-glycosylated protein containing 172 amino-acid residues.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 7124-10 10009-156 Each (10µG) Retrieving Restricted
50 μg 7124-50 10009-158 Each (50µG) Retrieving Restricted
restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

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SPECIFICATIONS

Protein/Peptide Name SCD23
Protein Synonyms CD23 antigen, BLAST-2, Fc-epsilon-RII, Lymphocyte IgE receptor Lymphocyte IgE receptor, Fc-epsilon-RII, CD23 antigen, BLAST-2
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Purity ≥96%
Endotoxin Content < 0.1 ng/μg of protein (<1EU/μg).
Molecular Weight 19.2 kDa
Formulation Sterile filtered through a 0.2 micron filter. Lyophilized from 0.5X PBS, pH 8.0.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Protein Type Recombinant
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