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sCD22, Human Recombinant, BioVision

Supplier: BioVision
>98% Pure active Human Recombinant sCD22.

Determined by its ability to inhibit the proliferation of Raji cells. The expected ED50 for this effect is 10-17 μg/ml.

CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand. Recombinant human CD22 is a soluble 75.0 kDa protein which corresponds to the extracellular domain of CD22.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 7123-10 10009-152 Each (10µG) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

50 μg 7123-50 10009-154 Each (50µG) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
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* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

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SPECIFICATIONS

Protein/Peptide Name Scd22
Protein Synonyms B-Lymphocyte cell adhesion molecule, Leu-14 Leu-14, B-Lymphocyte cell adhesion molecule
Protein/Peptide Type Recombinant
Species Human
Source CHO cells
Purity ≥98%
Endotoxin Content < 0.1 ng/μg of protein (<1EU/μg).
Molecular Weight ~75 kDa
Formulation Sterile filtered through a 0.2 micron filter. Lyophilized from 1X PBS, pH 7.2.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Protein Type Recombinant
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