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Cardiotrophin-1, Murine Recombinant, BioVision

Supplier: BioVision
>98% Pure active Murine Recombinant Cardiotrophin 1

Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.

CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Recombinant murine Cardiotrophin-1 is a 21.3 kDa protein consisting of 202 amino acid residues.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 7121-10 10009-144 Each (10µG) Retrieving Restricted
50 μg 7121-50 10009-146 Each (50µG) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name Cardiotrophin Cardiotrophin 1
Protein Synonyms CT-1
Protein/Peptide Type Recombinant
Species Mouse
Source E. coli
Purity ≥98%
Endotoxin Content < 0.1 ng/μg of protein (<1EU/μg).
Molecular Weight 21.3 kDa
Formulation Sterile filtered through a 0.2 micron filter. Lyophilized from 0.5 mg/ml in 5 mM Tris, pH 8.0
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Protein Type Recombinant
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