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APRIL, Human Recombinant, BioVision

Supplier: BioVision
7117-50 7117-10
>95% Pure active Human Recombinant APRIL.

Determined by its ability to induce cell death in Jurkat cells.

APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor. Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 7117-10 10009-128 Each (10µG) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Shipping duration cannot exceed 2 days.

50 μg 7117-50 10009-130 Each (50µG) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Shipping duration cannot exceed 2 days.

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SPECIFICATIONS

Protein/Peptide Name APRIL
Protein Synonyms TNFSF13, TRDL-1a
Protein/Peptide Type Recombinant
Species Human
Source Hi-5 Insect cells
Purity ≥95%
Endotoxin Content < 0.1 ng/μg of protein (<1EU/μg).
Molecular Weight 16.3 kDa
Formulation Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.5, 500 mM NaCl and 5% Trehalose.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-0.5 mg/ml.
Protein Type Recombinant
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