Human Recombinant Amphiregulin (from E. coli)

Supplier: BioVision
7114-10 7114-50
10009-118EA 350.25 USD
10009-118 10009-116
Human Recombinant Amphiregulin (from E. coli)
>95% Pure active Human Recombinant Amphiregulin.

Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells.
The expected ED50 for this effect is 5-10 ng/ml.

Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR