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IL-36γ, Human Recombinant, BioVision

Supplier: BioVision
>98% Pure active Human Recombinant IL-36γ.

Measured by its ability to induce IL-8 production by human PBMCs

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36 α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant human IL-36γ is a 17.0 kDa protein containing 152 amino acid residues.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 7111-10 10009-104 Each (10µG) Retrieving Restricted
50 μg 7111-50 10009-106 Each (50µG) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name Ilamma
Protein Synonyms IL-1E, IL-1F9, epsilon, IL-1H1, IL-1F IL-1F9, IL-1E, epsilon, IL-1H1, IL-1F
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Purity ≥98%
Endotoxin Content < 0.1 ng/μg of protein (<1EU/μg).
Molecular Weight 17.0 kDa
Formulation Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.0 and 50 mM NaCl.
Reconstitution Instructions Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Protein Type Recombinant
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