Human Recombinant IL36RA (from E. coli)

Supplier: BioVision
7109-50 7109-10
10009-098EA 671.3 USD
10009-098 10009-096
Human Recombinant IL36RA (from E. coli)
>98% Pure active Human Recombinant IL-36RA.

Measured by its ability to inhibit IL-36γ induced IL-6 production by human PBMCs

The IL-1 family is comprised of 11 structurally related ligands, including the recently re-named IL-36RA (IL-1F5), IL-36α (IL-1F6), IL-36β (IL-1F8), and IL-36γ (IL-1F9). The interaction of IL-36 ligands with the IL-1Rrp2 receptor (IL-1R6) can induce various activities, including dendritic cell maturation and activation. IL-36RA can antagonize the NF-kappaB signaling induced by either IL-36α, -β or -γ by binding to the IL-1Rrp2 receptor in a manner that prevents the initiation of functional signaling. Recombinant human IL-36RA is an E. coli derived 17 kDa protein containing 154 amino acid residues.
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