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IL-36RA, Human Recombinant, BioVision

Supplier: BioVision
>98% Pure active Human Recombinant IL-36RA.

Measured by its ability to inhibit IL-36γ induced IL-6 production by human PBMCs

The IL-1 family is comprised of 11 structurally related ligands, including the recently re-named IL-36RA (IL-1F5), IL-36α (IL-1F6), IL-36β (IL-1F8), and IL-36γ (IL-1F9). The interaction of IL-36 ligands with the IL-1Rrp2 receptor (IL-1R6) can induce various activities, including dendritic cell maturation and activation. IL-36RA can antagonize the NF-kappaB signaling induced by either IL-36α, -β or -γ by binding to the IL-1Rrp2 receptor in a manner that prevents the initiation of functional signaling. Recombinant human IL-36RA is an E. coli derived 17 kDa protein containing 154 amino acid residues.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 7109-10 10009-096 Each (10µG) Retrieving Restricted
50 μg 7109-50 10009-098 Each (50µG) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name IL36RA
Protein Synonyms IL-1RP3, IL-1F5, IL-1HY1, IL-1L1, IL-1ra Homolog 1, FIL1 delta, IL-1 delta IL-1 delta, IL-1F5, IL-1L1, IL-1ra Homolog 1, FIL1 delta, IL-1HY1, IL-1RP3
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Purity ≥98%
Endotoxin Content < 0.1 ng/μg of protein (<1EU/μg).
Molecular Weight 17 kDa
Formulation Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.5.
Reconstitution Instructions Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Protein Type Recombinant
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