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Human CellExp™ VEGF 165, Human Recombinant, BioVision

Supplier: BioVision
>95% Pure HEK 293 cells expressed Human recombinant VEGF 165

ED₅₀ is typically 2 to 10 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of HUVEC cells (Human Umbilical Vein Endothelial Cells).

VEGF is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/ macrophage migration, neurons, cancer cells, kidney epithelial cells).VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 µg 6485-10 10008-540 Each (10µG) Retrieving Restricted
50 µg 6485-50 10008-542 Each (50µG) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name VEGF VEGF165
Protein Synonyms VEGF, MGC70609, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen Folliculostellate cell-derived growth factor, VEGF, MGC70609, Glioma-derived endothelial cell mitogen
Protein/Peptide Type Recombinant
Species Human
Source 293 cells
Gene ID 7422
Purity > 95%
Endotoxin Content < 1.0 EU per 1 μg of protein
Molecular Weight 45 kDa
Formulation Lyophilized in PBS.
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Protein Type Recombinant
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