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Human CellExp™ TNF-alpha, Human Recombinant, BioVision

Supplier: BioVision
>95% Pure HEK 293 cells expressed Human recombinant TNF-alpha

ED₅₀ is typically < 0.9 ng/mL. The specific activity was determined by the dose-dependent cytotoxity of the TNF alpha sensitive cell line L-929 in the presence of Actinomycin D.

Tumor Necrosis Factor-α (TNF-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. TNF is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 µg 6482-10 10008-528 Each (10µG) Retrieving Restricted
50 µg 6482-50 10008-530 Each (50µG) Retrieving Restricted
restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
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* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

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SPECIFICATIONS

Protein/Peptide Name TNF alpha
Protein Synonyms DIF, TNFA, Tumor necrosis factor ligand superfamily member 2, TNF-alpha, Cachectin, TNFSF2, TNF-a Tumor necrosis factor ligand superfamily member 2, TNFSF2, Cachectin, TNF-a, TNF-alpha, DIF, TNFA
Protein/Peptide Type Recombinant
Species Human
Source 293 cells
Purity > 95%
Endotoxin Content < 1.0 EU per 1 μg of protein
Molecular Weight 17 kDa
Formulation Lyophilized in PBS.
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Protein Type Recombinant
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