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Human CellExp™ IL-28B, Human Recombinant, BioVision

Supplier: BioVision
>95% Pure HEK 293 cells expressed Human recombinant IL-28B

ED₅₀ is typically 0.1 to 1 ng/mL. The specific activity was determined by the dose-dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus.

IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 µg 6472-10 10008-704 Each (10µG) Retrieving Restricted
50 µg 6472-50 10008-706 Each (50µG) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name IL28B
Protein Synonyms IL-28A, ZCYTO20, Cytokine ZCYTO20, IFNL2, Interleukin-28A, IFN-Lambda 2, IL28A, Interferon-Lambda 2 Interferon-Lambda 2, Interleukin-28A, IFNL2, Cytokine ZCYTO20, IL28A, IL-28A, ZCYTO20, IFN-Lambda 2
Protein/Peptide Type Recombinant
Species Human
Source 293 cells
Purity > 95%
Endotoxin Content < 1.0 EU per 1 μg of protein
Molecular Weight 24 kDa
Formulation Lyophilized in PBS.
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Protein Type Recombinant
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