CellExp™ Human Recombinant IL28B (from 293 Cells)

Supplier: BioVision
CellExp™
6472-10 6472-50
10008-706EA 1377.64 USD
10008-706 10008-704
CellExp™ Human Recombinant IL28B (from 293 Cells)
>95% Pure HEK 293 cells expressed Human recombinant IL-28B

ED₅₀ is typically 0.1 to 1 ng/mL. The specific activity was determined by the dose-dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus.

IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
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