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Human CellExp™ IL-17F, Human Recombinant, BioVision

Supplier: BioVision
6469-50 6469-10
>95% Pure HEK 293 cells expressed Human recombinant IL-17F

ED₅₀ is typically 100 to 500 ng/mL. The specific activity was determined by the dose-dependent induction of IL-6 secretion from NHDF Adult fibroblasts.

Interleukin-17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. IL17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL-17F is a member of the IL-17 family of structurally-related cytokines. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F stimulates proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 µg 6469-10 10008-692 Each (10µG) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Shipping duration cannot exceed 2 days.

50 µg 6469-50 10008-694 Each (50µG) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Shipping duration cannot exceed 2 days.

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SPECIFICATIONS

Protein/Peptide Name IL17F
Protein Synonyms Interleukin-17 AF, Interleukin-17 A/F, IL17 A/F, IL-17 A/F, IL17A/F, IL17AF, IL-17A/F, IL-17 AF IL-17A/F, IL-17 AF, IL17A/F, IL17 A/F, IL17AF, IL-17 A/F, Interleukin-17 AF, Interleukin-17 A/F
Protein/Peptide Type Recombinant
Species Human
Source 293 cells
Purity > 95%
Endotoxin Content < 1.0 EU per 1 μg of protein
Molecular Weight 38 kDa
Formulation Lyophilized in PBS.
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Protein Type Recombinant
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