Human CellExp™ IL-4, Human Recombinant, BioVisionSupplier: BioVision
10008-670EA 1364.72 USD10008-670 10008-668
Human CellExp™ IL-4, Human Recombinant, BioVision
Proteins and Peptides
>95% Pure HEK 293 cells expressed Human recombinant IL-4
ED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent simulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
IL4 is a pleiotropic cytokine and a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.