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Human CellExp™ IL-4, Human Recombinant, BioVision

Supplier: BioVision
>95% Pure HEK 293 cells expressed Human recombinant IL-4

ED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent simulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

IL4 is a pleiotropic cytokine and a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 μg 6463-10 10008-668 Each (10µG) Retrieving Restricted
50 μg 6463-50 10008-670 Each (50µG) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name IL4
Protein Synonyms Lymphocyte stimulatory factor 1, BSF-1, BCGF, B cell stimulating factor, BCDF BCGF, BCDF, Lymphocyte stimulatory factor 1, BSF-1, B cell stimulating factor
Protein/Peptide Type Recombinant
Species Human
Source 293 cells
Purity ≥95%
Endotoxin Content < 1.0 EU per 1 μg of protein
Molecular Weight 14 and 19 kDa
Formulation Lyophilized from a solution of 20 mM Tris-HCl, pH 7.4, with 300 mM NaCl.
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Protein Type Recombinant
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