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Human Recombinant Fumarase, BioVision

Supplier: BioVision
>95% Pure Active Recombinant Human Fumarase

Specific activity is > 1.0 unit/mg

Fumarase (Fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 μg 6384-100 10008-490 Each (100µG) Retrieving Restricted
restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
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  • City or County issued Business License
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* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

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SPECIFICATIONS

Enzyme Name Fumarase
Species Human
Source E. coli
Purity ≥95%
Molecular Weight 50.2 kDa
Formulation 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0).
Synonyms Fumarate hydratase, FH, HLRCC, LRCC, MCL, MCUL1
Type Recombinant
Endotoxin Content < 1.0 EU per 1 μg of protein (determined by LAL method)
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