Human Recombinant LDHA (from E. coli)

Supplier: BioVision
6374-100
10008-438EA 356.08 USD
10008-438
Human Recombinant LDHA (from E. coli)
>95% Pure Active Recombinant Human LDHA

Specific activity is >20 units/mg.

LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential.
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