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Human Recombinant GSTM2 (from E. coli)

Supplier: BioVision

Human Recombinant GSTM2 (from <i>E. coli</i>)

Human Recombinant GSTM2 (from <i>E. coli</i>)

AB168017-100UG

10008-392EA 881 USD

10008-392

Human Recombinant GSTM2 (from E. coli)

Proteins and Peptides

>95% Pure Recombinant Active Human GSTM2.

Specific activity is < 25 units/mg.

Glutathione S-transferase Mu 2 (GSTM2) belongs to the Glutathione S-Transferase (GST) family of proteins. There are 8 families of GST proteins: alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have various functions throughout the cell. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are structured in a gene cluster on chromosome 1p13.3 and are proven to be highly polymorphic. These genetic variants can change an individual's susceptibility to carcinogens and toxins as well as have an effect on the toxicity and efficacy of several drugs.

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