Human Recombinant Fkbp3 (from E. coli)

Supplier: BioVision
6342-100
10008-376EA 402.79 USD
10008-376
Human Recombinant Fkbp3 (from E. coli)
>90% Pure Recombinant Active Human FKBP3.

Specific activity is > 490 nmoles/min/mg.

FKBP3 is part of a family of immunosuppressant receptors which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 accelerates the folding of proteins. FKBP3 is part of the immunophilin protein family, which participates in immunoregulation and fundamental cellular processes concerning protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a greater affinity for rapamycin than for FK506 and therefore is a significant protein for immunosuppression by rapamycin.
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