Human Recombinant Follistatin (from E. coli)

Supplier: BioVision
4708-50 4708-100 4708-1000 4708-10
10007-006EA 706.34 USD
10007-006 10007-008 10007-012 10007-004
Human Recombinant Follistatin (from E. coli)
>95% Pure active Recombinant human Follistatin.

Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells. The expected ED₅₀ is 0.1-0.4 µg/ml in the presence of 7.5 ng/ml Activin A.

Follistatin belongs to a group of structurally-diverse diffusible proteins that binds to TGF-β ligands and inhibit their activity by hindering access to signaling receptors. This naturally occurring antagonist binds to Activin, BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids including 36 cysteine residues.
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