Prolactin Receptor, rat recombinant, BioVision

Supplier: BioVision

4991-10 4991-50 4991-1000
10006-974EA 165.09 USD
10006-974 10006-978 10006-976
Prolactin Receptor, rat recombinant, BioVision
Proteins and Peptides
>97% Pure active Recombinant rat Prolactin Receptor.

Determined by the dose-dependent inhibition of Prolactin stimulated proliferation of Nb2 cells and by high affinity binding of ovine Prolactin and other lactogenic hormones.

Prolactin is a pituitary hormone that plays a role in the stimulation of milk production, salt and H2O regulation, growth, development and reproduction. The primary step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. Prolactin is a hormone involved in a range of significant functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. Prolactin exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane Prolactin receptor. PRLR varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. Recombinant human Prolactin Receptor (Extra Cellular Domain) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 206 amino acids and having a molecular mass of 24.12 kDa.
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