>98% Pure active Recombinant human NT-3, a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells.
The ED₅₀ as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
NT-3 is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active form of human NT-3 is a dimer, formed by two identical 119 amino acid subunits, which is held together by strong hydrophobic interactions. The molecular mass is 13.6 kDa.