Mouse Recombinant HBEGF (from E. coli)

Supplier: BioVision
AB285541-1MG AB285541-10UG AB285541-50UG
10006-264EA 260.45 USD
10006-264 10006-268 10006-266
Mouse Recombinant HBEGF (from E. coli)
Proteins and Peptides
>95% Pure active mouse Recombinant HB-EGF.

The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is < 1.0 ng/ml, corresponding to a specific activity of > 1.0×106 units/mg.

HB-EGF is an EGF related growth factor which signals via the EGF receptor, and stimulates the proliferation of SMC (smooth muscle cells), fibroblasts, epithelial cells and keratinocytes. HB-EGF is expressed in various cell types and tissues, including vascular endothelial cells and SMC, macrophages, skeletal muscle, keratinocytes and particular tumor cells. HB-EGF’s ability to explicitly bind heparin and heparin sulfate proteoglycans is dissimilar from other EGF-like molecules, and might be related to the enhanced mitogenic activity, relative to EGF, that HB-EGF exerts on smooth muscle cells.
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