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IL-17A, human recombinant, BioVision

Supplier: BioVision
4176-25 4176-1000
>98% Pure active Recombinant Human Interleukin-17A (IL-17A).

The ED₅₀ as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts is < 2 ng/ml, corresponding to a specific activity of > 5 x 10⁵ units/mg.

The original described IL-17 protein, now known as IL-17A, was identified from a CD4+ T cells DNA library. IL-17 can be induced from primary peripheral blood CD4+ T cells upon stimulation. Supernatant from cells transfected with IL-17 induced IL-16 and IL-18 production and enhanced the surface expression of the intraCellular adhesion molecule-1 (ICAM-1) in human fibroblasts. Recombinant IL-17 is a 31 kDa disulfide-linked homodier of two 136 amino acid polypeptide chains.




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
1 mg 4176-1000 10006-248 Each (1mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

25 μg 4176-25 10006-250 Each (25µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

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SPECIFICATIONS

Protein/Peptide Name IL17A
Protein Synonyms IL-17A, IL-17A, IL17A, IL 17 A, h-IL-17A, rh-IL-17A, IL-17A
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Purity ≥98%
Endotoxin Content <0.1 ng/μg
Molecular Weight 31.0 kDa
Formulation Sterile filtered and lyophilized with no additives
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml.
Protein Type Recombinant
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